Figure 2
From: Variants in exons and in transcription factors affect gene expression in trans
Topological properties on a protein-protein interaction network versus exonic source-target association significance. Averages for (a) distance between source and target, (b) source degree and (c) target degree are evaluated across source-target pairs of candidate exon eSNPs at varying association p-value thresholds (+). The average of randomly permuted pairs (dashed horizontal line) is shown for permuted pairs and Spearman's rank correlation coefficient (denoted r) is listed when significant at P <0.05 (denoted p).