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Table 5 Sequencing technology error rates

From: Characterizing and measuring bias in sequence data

Data set

Fractional error rate

Sample

#

Platform

Mismatches

Deletions

Insertions

Total

P. falciparum

1

Illumina MiSeq

0.0046

0.00021

0.00011

0.0049

 

2

Ion Torrent PGM

0.0038

0.0090

0.0068

0.020

 

3

Pacific Biosciences RS

0.0068

0.033

0.14

0.18

E. coli

4

Illumina MiSeq

0.0036

0.0000097

0.0000051

0.0037

 

5

Ion Torrent PGM

0.0018

0.0053

0.0044

0.012

 

6

Pacific Biosciences RS

0.0077

0.032

0.17

0.21

R. sphaeroides

7

Illumina MiSeq

0.0030

0.000018

0.0000089

0.0030

 

8

Ion Torrent PGM

0.0014

0.0055

0.0037

0.011

 

9

Pacific Biosciences RS

0.0076

0.029

0.16

0.20

Human

14

Illumina HiSeq

0.0030

0.00023

0.00017

0.0034

 

15

Ion Torrent PGM

0.0060

0.0069

0.0057

0.019

 

16

Complete Genomics

0.023

0.000099

0.000091

0.024

  1. For a subset of the data sets in Table 2, we show the fractional rates of mismatch, deletion, and insertion, computed relative to coverage, inferred by comparison to the reference sequences. For human we note that bona fide differences between the sample and reference sequence were recorded as errors.
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Genome Biology

ISSN: 1474-760X

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