Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance

Table 4 Ontology enrichment analysis for drifting and converging pairs

GO term	Description	Adjusted P-value
Drifting pairs
GO:0032502	Developmental process	3.21E-12
GO:0048856	Anatomical structure development	8.34E-10
GO:0048869	Cellular developmental process	2.15E-09
GO:0048598	Embryonic morphogenesis	2.61E-07
GO:0009653	Anatomical structure morphogenesis	9.50E-07
GO:0007389	Pattern specification process	2.36E-06
GO:0050793	Regulation of developmental process	3.86E-06
GO:0007166	Cell surface receptor signaling pathway	5.33E-06
GO:2000026	Regulation of multicellular organismal development	1.06E-05
GO:0023051	Regulation of signaling	2.59E-05
Converging pairs
GO:0048856	Anatomical structure development	7.43E-08
GO:0032502	Developmental process	1.01E-07
GO:0048598	Embryonic morphogenesis	2.14E-05
GO:0050793	Regulation of developmental process	2.99E-05
GO:0022610	Biological adhesion	3.66E-05
GO:0007155	Cell adhesion	3.05E-05
GO:0045595	Regulation of cell differentiation	7.62E-05
GO:0048869	Cellular developmental process	1.95E-04
GO:0023051	Regulation of signaling	3.07E-04
GO:2000026	Regulation of multicellular organismal development	3.66E-04

The top ten Gene Ontology (GO) terms ranked by FDR (q values) ranked by mean delta discordance across 'drifting' and 'converging' pairs.