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Figure 2 | Genome Biology

Figure 2

From: CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes

Figure 2

MGE contig SRS016200_WUGC_scaffold_12207 represents a mosaic genomic island. The contig is 101,291 bp long, and is shown as an open box in the middle, with protospacers shown as vertical lines within the box (gray lines each show a protospacer that is similar to spacers from individual HMP datasets, while lines of the same color show sets of protospacers matching spacers all from the same HMP dataset). Similarities between this contig and two bacterial genomes, H. parainfluenzae T3T1 (with sequence identity of 93%) and H. parainfluenzae ATCC 33392 (with sequence identity of 97%), and one ICE (ICEhin1056 found in H. influenzae), are represented as green, blue and yellow shades, respectively, between the contig and the corresponding genome lines. The location of the tRNA-Leu gene found in the contig is highlighted by a red triangle. The prophage regions found in this contig by Prophage finder and PHAST are shown as red lines, below the contig box. The regions corresponding to the genomic island regions in the H. parainfluenzae T3T1 genome as predicted by various methods (IslandViewer, IslandPick, SIGI-HMM and IslandPath-DIMOB) are represented as blue lines above the corresponding genome line.

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