Figure 7From: Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitorsCorrelation of known PI3K, JAK and MEK pathway markers with responses to kinase inhibitors. (a) Correlation of phosphorylated peptides containing phosphorylation sites known to be downstream of PI3K/mTOR with sensitivity to PI-103. (b) Correlation of phosphorylated peptides on MARCKS, known to contain sites phosphorylated by PKCs, with responses to PI-103. (c) Correlation of phosphorylation sites on STAT5A, a known JAK site, and ribosomal S6 (RPS6 gene product) with sensitivity to JAK-i. (d). Correlation of several sites on stathmin (STMN1 gene product) with the sensitivity to MEK-i. Open squares: individual data points; filled diamonds: averages of individual data points.Back to article page