Figure 5

Population distribution of human gene retrocopy insertions. Rows represent self-described human populations with three-letter designations as used by the 1,000 Genomes Project. Columns represent 48 retrocopies. Open squares indicate the GRIP (row) was not detected in the population (column) and filled squares indicate that a GRIP was detected in the corresponding population at a frequency indicated by the color of the square. Hierarchical clustering of populations was performed using the Jaccard distance between each pair of insertion profiles. Population-specific GRIPs restricted to either single populations or groups with geographically similar ancestry are shown according to geographic locality. Correspondence between indicated geographic locations and columns representing allele frequencies is indicated by open, closed, or partially closed circles. ASW: African ancestry in south-west US; CEU: Utah residents with northern and western European ancestry; CHB: Han Chinese in Beijing, China; CHS: Han Chinese in southern China; CLM: Colombian in Medellin, Colombia; FIN: Finnish from Finland; GBR: British from England and Scotland; GRIP: gene retrocopy insertion polymorphism; JPT: Japanese in Tokyo, Japan; LWK: Luhya in Webuye, Kenya; MXL: Mexican ancestry in Los Angeles; PUR: Puerto Rican in Puerto Rico; TSI: Toscani in Italy; YRI: Yoruba in Ibadan, Nigeria