Figure 7
From: Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
Phosphorylation of serine residue 21 of EZH2 is increased following epithelial-mesenchymal transition. (A) Ingenuity Pathway Analysis showing inhibition of EZH2 as a potential upstream regulatory event following Twist-induced epithelial-mesenchymal transition. Overall, 37 target genes were predicted to be inhibited by EZH2. (B) Immunofluorescence showing increase of phosphorylation of EZH2 at serine residue 21 in human mammary epithelial (HMLE) Twist cells as compared to HMLE vector cells.