Figure 3
From: Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
H3K27me3 switches orchestrate a mesenchymal cell-type specific gene expression signature. (A) Venn diagram of genes marked by H3K27me3 in human mammary epithelial cells (HMLE) vector cells and HMLE Twist cells. (B) Landscape of H3K27me3 mark in CDH1 gene (gain of H3K27me3 mark in HMLE Twist cells). (C) Box-plot of gene expression (the bars represent 10% and 90% extremes) for genes switching in HMLE vector cells from H3K4me3, H3K27me3, bivalent or neither marks to other histone mark combinations in HMLE Twist cells.