Figure 2
From: Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
H3K4me3 dynamic modifications are coupled with transcriptional changes related to epithelial-mesenchymal transition genes. (A) Pie chart showing the distribution of H3K4me3 and H3K27me3 marks in human mammary epithelial cells (HMLE) vector cells and HMLE Twist cells. (B) Landscape of H3K4me3 for CDH1 (loss of H3K4me3 in vector cells) and ZNF75A (gain of H3K4me3) in HMLE Twist cells. (C) Venn diagram of H3K4me3 at gene promoters in HMLE vector cells and HMLE Twist cells. (D) Box plots for gene expression changes in genes losing or gaining the H3K4me3 mark. (E) Gene ontology analysis using DAVID for genes losing the H3K4me3 mark. The x-axis represents the P-value levels and y-axis the gene ontology pathways. (F) Gene ontology analysis using DAVID for genes gaining the H3K4me3 mark. The x-axis represents the P-value levels and y-axis the gene ontology pathways.