The evolution, impact and properties of exonic splice enhancers

Table 3 Purine content in and out of ESEs within the 50 bp at both exon ends

	Mean:ESE	Mean:non-ESE	Median:ESE	Median:non-ESE
ESR	0.5441842	0.5000044	0.5416667	0.5
INT2	0.6063711	0.4571333	0.6122449	0.4561404
INT2.400	0.6612339	0.4584617	0.6666667	0.4571429
INT3	0.7409292	0.4755146	0.75	0.4754098
INT3.400	0.7881002	0.4873524	0.8125	0.4871795
Ke-ESE	0.5532219	0.4672781	0.5529412	0.4655172
Ke-ESE400	0.6162153	0.4861662	0.6206897	0.484375
PESE	0.6167329	0.4687956	0.6190476	0.4693878
RESCUE	0.705773	0.4359836	0.7142857	0.4361702

We performed a paired Wilcoxon test for each exon comparing purine content in ESE and non-ESE. All tests are highly significant before and after Bonferonni correction and not shown.

ISSN: 1474-760X