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Table 4 Characteristics of the minimal CpG differential set for discrimination of the seven sarcoma clusters

From: Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas

Cluster comparison(a versus b) Short name CpG Gene symbol Area under curve (Mvalue) (%) Hypermethylation (binary) (%) Pairwise Wilcoxon test Pvalue Kruskal–Wallis Pvalue CpG region
  Cluster a Cluster b   
1–2 4-02 cg10062065 SPEG 100 0 100 4.7 × 10–5 7.3 × 10–4 P
1–3 1-02 cg16907566 COL14A1 90 0 23 1.2E-03 9.6 × 10–5 P
1–4 3-30 cg00250430 DMRT2 85 0 61 2.3E-03 1.2 × 10–4 P
1–5 1-01 cg22298088 NNAT 100 0 100 1.8 × 10–5 1.1 × 10–5 P
1–6 5-01 cg00201234 FBLN2 100 67 0 4.2 × 10–5 1.1 × 10–4 P
1–7 2-01 cg08397758 PYROXD2 100 100 0 8.4 × 10–6 3.2 × 10–4 P
2–3 4-02 cg10062065 SPEG 100 100 0 6.3 × 10–5 7.3 × 10–4 P
2–4 4-06 cg00476577 ZNF217 99 0 89 2.7 × 10–5 1.9 × 10–4 P
2–5 4-02 cg10062065 SPEG 100 100 0 9.1 × 10–5 7.3 × 10–4 P
2–6 4-02 cg10062065 SPEG 100 100 0 1.4 × 10–4 7.3 × 10–4 P
2–7 2-01 cg08397758 PYROXD2 100 100 0 2.9 × 10–4 3.2 × 10–4 P
3–4 3-07 cg10895543 CDKN2A 91 29 91 4.7 × 10–5 2.8 × 10–6 GB
3–5 1-01 cg22298088 NNAT 100 0 100 3.0 × 10–5 1.1 × 10–5 P
3–6 5-01 cg00201234 FBLN2 100 67 0 8.3 × 10–5 1.1 × 10–4 P
3–7 2-01 cg08397758 PYROXD2 100 100 0 2.0 × 10–5 3.2 × 10–4 P
4–5 1-01 cg22298088 NNAT 100 0 82 5.0 × 10–6 1.1 × 10–5 P
4–6 5-01 cg00201234 FBLN2 99 67 0 2.7 × 10–5 1.1 × 10–4 P
4–7 2-01 cg08397758 PYROXD2 100 100 0 2.0 × 10–6 3.2 × 10–4 P
5–6 1-01 cg22298088 NNAT 100 0 100 7.6 × 10–5 1.1 × 10–5 P
5–7 2-01 cg08397758 PYROXD2 100 100 0 3.0 × 10–5 3.2 × 10–4 P
6–7 2-01 cg08397758 PYROXD2 100 100 0 4.2 × 10–5 3.2 × 10–4 P
  1. GB, gene body; P: promoter.