Skip to main content
Figure 7 | Genome Biology

Figure 7

From: Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation

Figure 7

Post‐transcriptional improvement of complex subunit co‐regulation. (A) Subunits of annotated protein complexes (red) are significantly more co‐regulated than random protein pairs (green). (B) Subunits of protein complexes are significantly more co‐regulated on the protein level (red) than on the transcript level (light red). The random protein pairs are indicated in dark green, random transcript pairs in light green. (C) Matrix of P values of significantly co‐regulated protein complexes (DPiM) [39] at the mRNA level and at the protein level. The complexes are numbered according to DPiM since several of them have neither names nor known biological functions. The individual complex members are listed in Additional file 4. The color intensity indicates increasing significance. P values were determined by the Kolmogorov–Smirnov test (KS‐test) and corrected for multiple testing. DPiM, Drosophila protein interaction map.

Back to article page