Figure 2

The majority of genes are subject to XCI. XCI status in individual informative females with each column representing one gene (only genes with at least one informative female are included) and each row a single female (group 1 and group 2 females only) from the three sample sets. The XCI status of each female is either subject to XCI (red) or escapes from XCI (E₃, light green; E₂, bright green; E₁, dark green). For how AIs were converted into XCI status, see Additional files 2, 5, 9 and 12. The genic XCI status was determined by calculating the percentage of females that escaped from XCI for each gene. Subject to XCI (red: 0 to 22% of informative females escaped from XCI), variable escape from XCI (purple: 22 to 78% of informative females escaped from XCI) and escape from XCI (green: 78 to 100% of informative females escaped from XCI). An ideogram of the X chromosome is shown with 25 Mb regions shown with grey dotted lines.