Figure 2

Performance of Open-Phylo using the casual or expert version of the Phylo video game. Ratio of puzzles improved by Open-Phylo for the scoring functions Ancestor (top left), MUSCLE (top right), GUIDANCE (bottom right) and T-Coffee (bottom left). The alignment program used to calculate the initial MSAs is indicated on the axis of the radar charts: Multiz (north), MUSCLE (west), PRANK (south) and T-Coffee (east). The area surrounded by a blue line corresponds to the performance achieved with the casual puzzles only, while the area surrounded by a red line indicates the performance of the expert version only. The area surrounded by a dashed green line shows the ratio of alignments improved by either the classic or expert version.