Table 2 Metrics for simulating normal contamination in tumor and normal genome FASTA files
From: The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models
SNP density | Type | Millions of reads | |||
|---|---|---|---|---|---|
Normal | Tumor content | ||||
| Â | 30% | 60% | 100% | ||
0 | Normal | 8 | 5.6 | 3.2 | 0 |
| Â | Tumor | 0 | 2.4 | 4.8 | 8 |
0.001 | Normal | 8 | 5.6 | 3.2 | 0 |
| Â | Tumor | 0 | 2.4 | 4.8 | 8 |
0.01 | Normal | 8 | 5.6 | 3.2 | 0 |
| Â | Tumor | 0 | 2.4 | 4.8 | 8 |
0.1 | Normal | 8 | 5.6 | 3.2 | 0 |
| Â | Tumor | 0 | 2.4 | 4.8 | 8 |
0.5 | Normal | 8 | 5.6 | 3.2 | 0 |
| Â | Tumor | 0 | 2.4 | 4.8 | 8 |