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Table 1 Study set overview

From: The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

Genotype

Samples

mitf:BRAF V600E

1

mitf:BRAF V600E ;p53 +/-

2

mitf:BRAF V600E ;p53 +/- ; ptena hu1874 +/-

1

mitf:BRAFV600E;mitf vc7+/+;

4

mitf:BRAFV600E;mitf vc7+/+;p53+/-

4

mitf:BRAFV600E; p53-/-;mitf -/-;mitf:MITF

6

mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:foxd3

4

mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:krox20

12

mitf:BRAFV600E;p53-/-;mitf -/-mitf:MITF;mitf:krox20/foxd3/OCT6*

1

mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:SETDB1

1

mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:EGFP

1

mitf:NRAS1 Q61K

2

mitf:NRAS1 Q61K ;p53 -/-

5

mitf:NRAS1 Q61K ;p53 +/-

4

mitf:NRAS1 Q61K ;p53 +/- ;rps29 +/-

5

Total

53

  1. The asterisk indicates that the genes krox20, foxd3 and OCT6 were each expressed on separate plasmids for this tumor.