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Table 1 Demographic, clinical and histological characteristics of the samples

From: Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

Characteristics Diseased Healthy P-value
n 12 14
Age (years) mean ± SD 68.0 ± 10.81 61.14 ± 11.2 0.11
Ethnicity    
Asian, Pacific Islander 0 1  
White, non-Hispanic 4 2  
Black, non-Hispanic 4 4  
Hispanic 1 3  
Other and unknown 3 4  
Height (cm) mean ± SD 165 ± 8.69 166.5 ± 8.63 0.6
Weight (kg) mean ± SD 78.0 ± 22.02 88.32 ±15.93 0.2
BMI (kg/m2) mean ± SD 27.85 ± 6.41 31.25 ± 5.58 0.18
Diabetes 6 5  
Hypertension 11 12  
Proteinuria (dipstick) 3.0 ± 1.83 0.36 ± 0.81 1.80E-04
Serum BUN (mg/dL) mean ± SD 35.0 ± 14.7 17.71 ±5.85 4.60E-04
Serum creatinine (mg/dL) mean ± SD 3.0 ± 1.61 1.08 ± 0.18 2.00E-03
eGFR (ml/minute/1.73 m2) mean ± SD 29.0 ± 13.68 70.94 ± 8.35 1.06E-09
Histology    
Glomerulosclerosis (%) 31.0 ± 31.35 3.31 ±5.52 4.00E-03
Mesangial matrix expansion 1 ± 0.91 0.17 ± 0.39 0.03
Tubular atrophy (%) 34.0 ± 24.94 9.82 ± 15.76 6.00E-03
Interstitial fibrosis (%) 34.0 ± 25.15 5.68 ± 5.07 4.00E-04
Vascular sclerosis    
Intima 2.0 ± 0.78 0.9 ± 1.1 1.50E-03
Arterioles 2.0 ± 0.78 0.29 ± 0.62 4.00E-04
  1. eGFR, estimated glomerular filtration rate; SD, standard deviation.