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Table 3 TCF7L2 cell type-specific modules

From: Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3

Cell line

Top four co-localized motifs

HCT116

AP1, CTCF, NF-E2, SP1

HEK293

HOXC9, CDX2, PDX1, FOXA1

HepG2

HNF4α, FOXA2, ERRα, PPARγ

HeLa-S3

ERG, MAZ, CEBP, NF-E2

MCF7

GATA3, AP2, TEAD, AP1

PANC1

CDX2, FOXA1, TEAD, RUNX2

  1. The sets of TCF7L2 binding sites specific for each cell line (not found in any of the other five cell lines) were analyzed using HOMER. The top four most highly enriched motifs (as determined by P-value), not including the TCF7L2 motif, are shown for each cell line.
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Genome Biology

ISSN: 1474-760X

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