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Table 3 TCF7L2 cell type-specific modules

From: Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3

Cell line Top four co-localized motifs
HCT116 AP1, CTCF, NF-E2, SP1
HEK293 HOXC9, CDX2, PDX1, FOXA1
HepG2 HNF4α, FOXA2, ERRα, PPARγ
HeLa-S3 ERG, MAZ, CEBP, NF-E2
MCF7 GATA3, AP2, TEAD, AP1
PANC1 CDX2, FOXA1, TEAD, RUNX2
  1. The sets of TCF7L2 binding sites specific for each cell line (not found in any of the other five cell lines) were analyzed using HOMER. The top four most highly enriched motifs (as determined by P-value), not including the TCF7L2 motif, are shown for each cell line.
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Genome Biology

ISSN: 1474-760X

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