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Table 2 Pseudogene biotypes

From: The GENCODE pseudogene resource

Biotype Definition
Processed pseudogene Pseudogene created via retrotransposition of the mRNA of a functional protein-coding parent gene followed by accumulation of disabling mutations
Duplicated pseudogene Pseudogene created via genomic duplication of a functional protein-coding parent gene followed by accumulation of disabling mutations
Unitary pseudogene Pseudogene for which the ortholog in a reference species (mouse) is coding but the human locus has accumulated fixed disabling mutations
Polymorphic pseudogene Locus known to be coding in some individuals but with disabling mutations in the reference genome
IG pseudogene Immunoglobulin gene segment with disabling mutations
TR pseudogene T-cell receptor gene segment with disabling mutations