Functional analysis of transcription factor binding sites in human promoters

Table 3 Summary of genes regulated by ubiquitously functional TFBSs for five TFs: CTCF, GABP, GATA2, STAT1, and YY1

A composite of RefSeq [104], UCSC known genes [105] and GENCODE [106] annotations were used. The GREAT gene annotation tool [107] was used to compare our data with results from published experiments: a targets of CREB, identified by ChIP-chip in HEK293T cells in three different time points after forskolin stimulation [81], b genes upregulated by tamoxifen [108] in HMEC-E6 cells, genes upregulated in Jurkat cells by IFN-α and IFN-β but not by overexpression of a constitutively active form of IRF3 [109], c targets of YY1 identified by Chip-chip [77], d targets of HNF4α identified by Chip-chip in hepatocytes from TF targets.

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