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Table 3 Enriched gene ontology categories in genic CNVs

From: Novel origins of copy number variation in the dog genome

P-valuea    Number of genes  
All CNVs Deletions Duplications GO ID Domain All Deletions Duplications Gene ontology term
9.48e-02 - 3.12e-03 GO:0032787 BP 5 0 5 1. Monocarboxylic acid metabolic process
5.00e-06 6.32e-04 1 GO:0022610 BP 14 7 1 1. Biological adhesion
5.00e-06 6.32e-04 1 GO:0007155 BP 14 7 1 2. Cell adhesion
2.67e-11 1.36e-06 1 GO:0016337 BP 14 7 1 3. Cell-cell adhesion
7.31e-13 2.37e-07 1 GO:0007156 BP 14 7 1 4. Homophilic cell adhesion
3.56e-03 6.29e-02 1 GO:0071944 CC 18 8 2 1. Cell periphery
2.68e-04 1.76e-01 1 GO:0016020 CC 47 16 20 1. Membrane
2.15e-03 4.88e-02 1 GO:0005886 CC 18 8 2 2. Plasma membrane
3.37e-04 6.08e-01 3.64e-01 GO:0044425 CC 40 13 19 1. Membrane part
8.74e-05 2.49e-01 3.45e-01 GO:0031224 CC 39 13 18 2. Intrinsic to membrane
6.07e-05 2.17e-01 2.92e-01 GO:0016021 CC 39 13 18 3. Integral to membrane
5.97e-02 1 3.82e-02 GO:0004872 MF 16 4 12 1. Receptor activity
- 1 2.66e-02 GO:0038023 MF 18 3 11 2. Signaling receptor activity
1.96e-02 1 1.27e-02 GO:0004888 MF 16 3 11 3. Transmembrane signaling receptor activity
1.49e-03 1 5.21e-04 GO:0004930 MF 15 3 11 4. G-protein coupled receptor activity
6.22e-06 1 9.88e-06 GO:0004984 MF 12 2 9 4. Olfactory receptor activity
3.18e-04 7.11e-05 1 GO:0005509 MF 17 10 1 1. Calcium ion binding
5.20e-01 - 9.98e-03 GO:0005506 MF 6 0 6 1. Iron ion binding
5.04e-03 1 6.44e-03 KEGG:04740 ke 7 1 5 1. Olfactory transduction
  1. aSignificant P-values are in bold. P-values were determined using a hierarchical multiple testing procedure. Indented numbers before the GO terms indicate relative depth of the term in the hierarchy. BP, biological process; CC, cellular component; MF, molecular function; ke, KEGG pathway.