Toward almost closed genomes with GapFiller

Table 3 Functional properties of gap closed regions

Annotation type	Total size in NC_000014 (bp)	Nucleotides closed with GapFiller (bp)	Portion of total nucleotides closed (%)
Gene	38,883,890	33,969	38.67%
mRNA	34,180,962	26,818	30.53%
CDS	29,380,348	23,617	26.89%
Other RNA	3,245,865	2,755	3.14%
V-segment	78,961	655	0.75%
C-region	36,984	23	0.03%
ncRNA	11,447	0	0%
Total	105,818,457	87,837	100.00%

Functionalities associated with the nucleotides incorporated with GapFiller based on the annotation of human chromosome 14. Clearly the method can add valuable sequence information to a number of functionalities present in GenBank:NC_000014. Most nucleotides are incorporated in coding sequence (CDS) and mRNA regions. ncRNA, non-coding RNA.

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