Figure 4

Comparison of the transcriptomes, proteomes, and phenomes of E. coli B REL606 and E. coli K-12 MG1655 cultured in LB medium. In the individual thumbnail graphs, the x-axes denote exponential and stationary growth phases, and the y-axes show the transcription ratio (on a log₂ scale) of each gene in the B strain to that of the homologous gene in the K-12 strain. The transcription bars are coded red for up-regulation in B and green for up-regulation in K-12. Genes showing differences in transcriptional (or translational) levels of ≥2- or ≤0.5-fold in the exponential and/or stationary phase(s) are shown. The backgrounds of the graphs are grey if both transcriptional and translational differences were detected. Gene names are shown in red if the translational level was higher in the B strain and green if it was higher in K-12. The top of the figure shows extracellular proteins with more than a two-fold difference between the strains in the stationary phase on growth in minimal medium. Significant differences in cell growth on particular carbon sources, demonstrated by phenotype microarray tests, are shown at the bottom. Growth curves are green for B, red for K-12, and yellow for the overlapping region. Abbreviations are given in Additional file 1.