From: A systematic screen reveals new elements acting at the G2/M cell cycle control
Gene | Cell length at divisiona (μm) | CVb (%) | Cell widthc (μm) | Cell volumed (μm3) | Doubling timee (min) | Molecular function | Biological process | S. cerevisiaeorthologs |
---|---|---|---|---|---|---|---|---|
wee1 | 7.4 ± 0.7 | 9.5 | 4.1 ± 0.2 | 80.5 ± 12.6 | 214 ± 10.4f | Protein kinase | G2/M transition | SWE1 |
pka1 | 10.5 ± 0.7 | 6.7 | 4.7 ± 0.2 | 153 ± 20.8 | 159 ± 2.3 | cAMP-dependent protein kinase | Glucose sensing/cAMP signaling | TPK1, TPK2, TPK3 |
gpa2 | 10.9 ± 0.9 | 8.3 | 4.5 ± 0.3 | 151.9 ± 18 | 181 ± 1.3 | G protein, α-subunit |  | GPA2 |
git5 | 12.9 ± 0.9 | 7.0 | 4.5 ± 0.2 | 179.6 ± 17.3 | 142 ± 4.9 | G protein, β-subunit |  | STE4 |
git3 | 12.7 ± 0.8 | 6.3 | 4.6 ±0.2 | 183.9 ± 24.8 | 145 ± 3.8 | G-protein coupled receptor |  | GPR1 |
zfs1 | 12.3 ± 0.7 | 5.7 | 4.1± 0.2 | 142.7 ± 13.6 | 140 ± 4.1 | RNA binding | mRNA degradation | CTH1, TIS11 |
ski3 | 12.4 ± 0.6 | 4.8 | 4.3 ± 0.2 | 162.2 ± 15.1 | 135 ± 1.6 | SKI complex component |  | SKI3 |
clp1 | 11.9 ± 0.9 | 7.6 | 4.4 ± 0.2 | 157.7 ± 15.8 | 138 ± 0.7 | Protein phosphatase | G2/M transition cytokinesis | CDC14 |
pom1 | 12.3 ± 1.6 | 13.0 | 4.5 ± 0.2 | 174.1 ± 31.1 | 141 ± 5.3 | Protein kinase |  |  |
nif1 | 12.5 ± 0.7 | 5.6 | 4.3 ± 0.2 | 159.6 ± 15.2 | 128 ± 2.3 | Protein kinase inhibitor | G2/M transition | DSF2 |
snf5 | 12.6 ± 0.7 | 5.6 | 4.3 ± 0.2 | 163.8 ± 15.9 | 135 ± 1.6 | SWI/SNF subunit | Chromatin remodeling | SNF5 |
sol1 | 12.9 ± 0.9 | 7.0 | 4.3 ± 0.2 | 162.9 ± 19.6 | 135 ± 4.4 | SWI/SNF subunit |  | SWI1 |
sgf73 | 12.7 ± 0.8 | 6.3 | 4.2 ± 0.3 | 157.0 ± 20.9 | 159 ± 5.1 | SAGA subunit | Histone modification | SGF73 |
pab2 | 13.1 ± 0.8 | 6.1 | 4.3 ± 0.2 | 165.7 ± 19.3 | 143 ± 4.7 | RNA binding | mRNA poly(A) tail length | SGN1 |
SPBC19F8.02 | 12.6 ± 0.6 | 4.8 | 4.3 ± 0.2 | 160.6 ± 14.1 | 134 ± 1.5 | NA | NA |  |
SPAC27E2.03c | 12.3 ± 0.7 | 5.7 | 4.3 ± 0.2 | 160.3 ± 18.4 | 157 ± 6.1 | GTP binding | NA | OLA1 |
ppa2 | 11.2 ± 1.0 | 8.9 | 4.3 ± 0.2 | 139.7 ± 15.9 | 136 ± 1.2 | Protein phosphatase | Signal transduction | PPH21, PPH22 |
pyp1 | 11.3 ± 0.6 | 5.3 | 4.7 ± 0.2 | 166.2 ± 15.8 | 143 ± 4.7 | Protein phosphatase | Stress-response MAPK cascade | PTP2, PTP3 |
WT | 14.1 ± 0.8 | 5.7 | 4.5 ± 0.2 | 199.4 ± 21.8 | 129 ± 2.2 |  |  |  |