Figure 2

Number of regulated splicing and PTC occurrences in Upf2 KO tissues. (a) Splice junctions with a minimum of three reads in WT or KO samples were grouped into upregulated (≥2-fold up in KO), downregulated (≥2-fold down in KO) or unregulated. Genes corresponding to the junctions are also shown. Left: number of junctions and genes and percentage in parentheses for the relative fraction in each tissue. The top half of the table lists results for all junctions, the bottom half for PTC+ junctions only. Right: pie charts visualize the relative distribution of regulated junctions and corresponding genes. (b) Venn diagram of major Gene Ontology terms associated with liver-unique genes (top), BMM-unique genes (bottom) and common genes (overlap).