Figure 7

Structural predictions of TF DNA binding domains. To date, we have created 212 structural predictions of the active sites of select TFs in TFe. We focused on TFs for which a structural prediction is most feasible and whose articles are nearing completion. These predictions were generated with an in-house, custom-made pipeline that finds the most similar, experimentally determined protein structure for each unsolved TF, and uses that experimentally determined 'template' to guide the prediction of the unknown structure.