The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome

Table 4 Haploinsufficient loci with developmental or cellular phenotypes not associated with strong haplolethality or haplosterility

Gene	Location	Phenotype	Reference^a
N	3C7-9	Wing notching	[47]
Hup ^b	7BC	Pronotal outgrowth	[48]
run	19E2	Segmentation defects	[49]
S	21E4	Eye roughness	[50]
Pkd2	33E3	Reduced smooth muscle contractility	[51]
b	34D1	Darker body color	[52]
Mhc	36B1	Muscle defects	[53]
lok	38B2	No apoptosis after telomere loss	[54]
vg	49E1	Wing notching	[55]
Np/CG34350 ^c	45A1	Notopleural bristle length	[56]
Pcl	55B8	2nd to 1st leg transformation	[57]
bs ^d	60C6	Wing venation defects	[58]
Dll	60E2	Antenna to leg transformation	[59]
Kr	60F5	Segmentation defects	[60]
mtrm	66C11	Increased female nondisjunction	[61]
Pc	78C6-7	2nd to 1st leg transformation	[62]
Scr	84A5	1st to 2nd leg transformation	[63]
Tm2	88E13	Muscle defects	[64]
Act88F	88F5	Muscle defects	[65]
Ubx	89D9	Haltere to wing transformation	[66]
Dl	92A1-2	Wing venation defects	[67]
bnl	92B2-3	Abnormal tracheal branching	[68]
H	92F3	Bristle shaft to socket transformation	[33]
e	93C7-D1	Darker body color	[48]
p53	94D10	No apoptosis after telomere loss	[54]
Mlc2	99E1	Muscle defects	[69]

^aReference originally describing haploinsufficiency. ^bHumeral patch (Hup) is the only locus in this list not mapped to a specific transcription unit. ^cAllelism of Notopleural (Np) and CG34350 demonstrated by Laurence von Kalm (personal communication). ^dPlexate (Px) is a haploinsufficient locus closely linked or allelic to blistered (bs) with similar phenotypes. We have assumed allelism.

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