In vivo binding specificity of SRSF3 and SRSF4. (a, b) The frequency distribution of SRSF3 (a) and SRSF4 (b) pentamer Z-scores. The Z-score was calculated relative to randomized genomic positions by shuffling the crosslink positions 100 times within the genes. Five pentamers with highest Z-scores are shown. (c) Correlation of SRSF3 and SRSF4 pentamer Z-scores. The top five pentamers presented in (a, b) are marked as larger light grey dots. (d) Consensus motifs were derived from the top pentamers shown in (a, b).