Figure 2From: Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome coxidase Localization of the predicted COX assembly factors in human mitochondria. The figure shows co-localization of AURKAIP1, C7orf44, C12orf62 and PET117 proteins with the mitochondrial marker tetramethyl rhodamine methyl ester (TMRM). We performed live cell imaging of HEK293 cells expressing GFP-tagged genes (left panels) loaded with the mitochondrial marker TMRM (middle panels). Superimposed images are shown on the right. Yellow indicates the GFP-TMRM overlap.Back to article page