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Figure 1 | Genome Biology

Figure 1

From: Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome coxidase

Figure 1

Ortho-Profile, the three-phase method for identifying distant orthologs. Orthologous human and fungal proteins were determined by means of bi-directional best hits at the sequence-to-sequence, profile-to-sequence and HMM-to-HMM levels. The pipeline detects distant orthologs owing to increasingly sensitive methods applied in subsequent phases (see Materials and methods for details).

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Genome Biology

ISSN: 1474-760X

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