Figure 1

Widespread changes in microRNA abundance with quiescence. (A) The log₂ fold-change in the expression of the 142 microRNAs that change expression at a 1% FDR during serum starvation (SS) or contact inhibition (CI) are depicted with respect to their average expression in proliferating (P) cells. Blue and yellow indicate negative and positive values, respectively. Genes are in order of the magnitude of their mean log₂ fold change from proliferation to quiescence. (B) 'Volcano' plot of microRNA average log₂ fold-change in quiescence conditions on the x-axis versus the log₁₀ P value for the significance of the quiescence parameter in gene expression on the y-axis.