Microevolutionary analysis of Clostridium difficile genomes to investigate transmission

Table 1 Properties of the 15 groups highlighted in Figure 1a

Group	STs	Counts	min(d)^a	max(d)^a	mean(d)^a	Mut^b	Rec^c	Sub^d	r/m^e
1	11	31	0	285	46	166	61	865	5.22
2	5,22	9,5	0	1,202	614	364	49	1,364	3.75
3	37	18	0	49	22	100	1	3	0.03
4	1	81	0	24	6	79	1	3	0.04
5	17	19	0	114	42	161	18	191	1.19
6	10	37	0	120	30	273	22	155	0.57
7	44	52	0	4,273	911	2,226	135	4,134	1.86
8	35	8	0	1,026	307	621	9	661	1.07
9	54,63	10,5	0	6,009	2,633	2,238	180	5,678	2.54
10	58	16	0	3,130	1,306	880	149	3,845	4.37
11	12,57	8,2	0	2,953	1,368	426	78	3,189	7.49
12	3	7	2	468	225	386	21	454	1.18
13	6,89	62,1	0	344	84	1,197	255	1,784	1.49
14	2,13,49,14	18,2,8,7	0	3,913	1,675	913	201	6,495	7.11
15	42	45	0	155	24	206	22	178	0.87

^ad is the pairwise distance between two genomes from different CDI cases. ^bEstimated number of mutation events. ^cEstimated number of recombination events. ^dEstimated number of substitutions introduced by recombination. ^eRatio of the effects of recombination versus mutation.

ISSN: 1474-760X