Distribution of the 1,518 detected proteins in developmental stages, subcellular compartments, and nuclear fractions. Detection of proteins in the various pools is depicted by Venn diagrams. Absolute numbers of proteins in each pool are indicated in brackets. (a) Protein distribution in ring stages, trophozoites, and schizonts. (b) Protein distribution in the cytoplasmic versus the combined nuclear fractions. (c) Protein distribution across the four nuclear fractions (DNAseI and high salt fractions were combined).