Meta-dataset creation process. Process of grouping specific selected profiles. (a) Press the green '+' (plus sign) toggle button to add samples to the 'Samples basket', and subsequently press the red '-' (minus sign) toggle button to remove samples. (b) In the samples basket, clinical annotations can be refined and standardized as explained in the 'Clinical annotations and biocuration' section. Additionally, samples can be removed using the 'tree view' actions. (c) To save, the user specifies a title, a summary and the desired privacy for the new dataset.