Figure 6

Annotation of differentially methylated CpGs. (a) Distance to TSS fordifferentially methylated CpGs are plotted from ER+ versus ER- analysis. (b) Pie chartshowing percentages of differentially methylated CpGs on promoters, exons, introns and intergenicregions. (c) Pie chart showing percentages of differentially methylated CpGs on CpG islands,CpG island shores (defined as 2kb flanks of CpG islands) and other regions outside of shores and CpGislands. (d) Pie chart showing percentages of differentially methylated CpGs on enhancers andother regions. ER+, estrogen receptor-alpha expressing; ER-, estrogen receptor-alpha non-expressing,TSS, transcription start site.