DNA methylation patterns and chromosomal distribution of three life stages of T. spiralis. (a) The fraction of mCs identified in each sequence context in the three life stages in comparison with the fraction of all Cs in each sequence context in the genome. (b) Distribution of MRs identified on the two DNA strands (Watson and Crick) throughout the whole genome. The value refers to the average percentage of methylation of the MRs, as shown on the y-axis. (c) Distribution of mCs (y-axis) across the percentage methylation levels (x-axis).