Figure 6

Examples of two high posterior eQTNs, rs473407 and rs28362527, in two genes. The first row shows the Bayes factors for each SNP located within a 35-kb window either side of the gene. The second row shows the position, and marginal enrichment level, of some of the regulatory annotations we analyzed here. The positions of the highest posterior SNPs in rows one and two are marked by yellow boxes. Row three shows independent data, not used by the hierarchical model, on the level of NF-κB binding in a 600-bp window centered on each of the two SNPs marked above in yellow, where the ChIP-seq profiles are grouped according to the genotypes at those SNPs. Data on between-individual variation in NF-κB binding were from [63]. TES, transcription end site.