Figure 2
From: Dissecting the regulatory architecture of gene expression QTLs
Estimated fold enrichment of eQTNs in putative regions of active chromatin. The plots show the enrichment of eQTNs within DNaseI hypersensitive peaks, or within regions marked by a number of histone modifications. (a) All locations within the cis region around each gene. Error bars show 95% confidence intervals. Arrows indicate that the confidence interval extends beyond the left end of the x-axis. (b) Open chromatin 5 to 100 kb upstream of the gene TSS. (c) Estimated probability that a random SNP is an eQTN as a function of distance from the TSS (grey bars) or the conditional probability of a random SNP being an eQTN, given that it lies outside or inside a DNaseI hypersensitive site, or within a DNaseI site overlapped by two or more histone marks.