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Table 3 Gene essentiality in models 1 and 3 at two threshold ratios (the highest percentage achieved for each prediction metric appears in bold)

From: MetaMerge: scaling up genome-scale metabolic reconstructions with application to Mycobacterium tuberculosis

 

Model 1 [13]

Model 3

Predictions in

Threshold 0.1

Threshold 0.2

Threshold 0.1

Threshold 0.2

True positive

106

139

49

63

False positive

97

64

40

26

True negative

325

285

508

436

False negative

56

96

129

201

Positive predictive value (%)

52

68

55

71

Negative predictive value (%)

85

75

80

68

Correct predictions (%)

74

73

77

69