Table 2 Gene Ontology categories significantly over-represented (P < 0.001) in ALIGATOR analysis
From: Implications for health and disease in the genetic signature of the Ashkenazi Jewish population
GO category | GO type | Genes in category | Genes on list | Expected on list | P-value | Expected hits per study | Function |
|---|---|---|---|---|---|---|---|
GO: 0031667 | Process | 89 | 22 | 9.69 | 0 | 0.06 | Response to nutrient levels |
GO: 0007584 | Process | 55 | 18 | 6.04 | 0 | 0.06 | Response to nutrient |
GO: 0005829 | Cellular | 856 | 135 | 98.43 | 0.00002 | 0.1 | Cytosol |
GO: 0051059 | Function | 22 | 10 | 2.37 | 0.00004 | 0.15 | NF-kappaB binding |
GO: 0009991 | Process | 100 | 23 | 10.42 | 0.00006 | 0.19 | Response to extracellular stimulus |
GO: 0030321 | Process | 6 | 5 | 0.94 | 0.00028 | 0.7 | Transepithelial chloride transport |
GO: 0006414 | Process | 83 | 10 | 2.91 | 0.00036 | 0.88 | Translational elongation |
GO: 0050957 | Process | 8 | 6 | 2.71 | 0.0007 | 1.69 | Equilibrioception |
GO: 0030127 | Cellular | 7 | 4 | 0.55 | 0.00086 | 2.07 | COPII vesicle coat |
GO: 0012507 | Cellular | 7 | 4 | 0.55 | 0.00086 | 2.07 | ER to Golgi vesicle membrane |