Accurate and fast estimation of taxonomic profiles from metagenomic shotgun sequences

Table 1 Comparison of sensitivity and precision.

Sequence length	Parameter	Taxonomic rank	MetaPhyler (%)	PhymmBL (%)	MEGAN (%)	WebCARMA (%)
60 bp	Sensitivity	Genus	33.45	18.18	15.49	22.66
		Family	54.22	38.75	24.52	25.10
		Order	59.59	49.36	31.74	28.22
		Class	70.72	62.86	50.78	32.12
		Phylum	75.30	68.88	64.19	34.65
	Precision	Genus	96.38	94.42	90.72	35.22
		Family	97.45	97.66	97.18	45.71
		Order	97.39	97.65	98.10	52.51
		Class	98.27	98.15	99.11	66.15
		Phylum	98.83	99.06	99.56	72.90
300 bp	Sensitivity	Genus	52.39	42.97	20.89	45.96
		Family	70.17	58.81	34.27	52.49
		Order	78.09	66.72	45.24	58.56
		Class	84.52	75.42	61.06	62.70
		Phylum	91.18	76.78	81.36	66.49
	Precision	Genus	97.90	96.16	96.09	77.63
		Family	99.14	99.07	99.19	88.69
		Order	99.15	99.15	99.21	92.67
		Class	99.34	99.34	99.57	95.43
		Phylum	99.64	99.64	99.80	96.58

ISSN: 1474-760X