First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum

Table 1 Summary of overall WDPMP exome sequencing

	Sample ID
	Tumor	Cell line	Normal
Raw reads	187,023,594	119,030,552	190,772,020
Unalignable reads	14,717,058	3,778,934	14,190,612
Aligned reads	172,306,536	115,251,618	176,581,408
Percentage alignable	92.13%	96.83%	92.56%
Reads passing filter	129,919,859	92,512,679	137,134,828
Percentage remaining after filter	69.47%	77.72%	71.88%
Number of PCR duplicates	8,498,978	15,903,654	6,070,718
Percentage PCR duplicates	6.54%	17.19%	4.43%
Reads within exome	80,042,870	49,312,008	80,869,734
Percentage reads overall in exome	61.61%	53.30%	58.97%
Percentage exome covered at 1×	97.10%	96.80%	97.00%
Percentage exome covered at 20×	86.80%	82.40%	86.30%

ISSN: 1474-760X