Figure 2From: Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegiaRelative amounts of mtDNA in skeletal muscle tissues from the patient and four control subjects. ND1/RNaseP and ND4/RNaseP ratios calculated by real-time quantitative PCR were used to evaluate mtDNA levels. The mtDNA level in the patient was comparable to those of controls. Values are relative to the average of all four controls.Back to article page