Figure 3

Sensitivity measurement of Exon Pilot SNP calls. Sensitivity was estimated by comparison to variants in HapMap, version 3.2, in regions overlapping the Exon Pilot exon targets. Circles connected with solid lines show the number of SNPs in such regions in HapMap, the Exon Pilot, and the Low Coverage Pilot project, as a function of alternative allele count. Dashed lines indicate the calculated sensitivity against the HapMap 3.2 variants. Sensitivity is shown for three sets of calls: the intersection between filtered call sets from BC and BI (most stringent); the union between the BC and BI filtered call sets; and the union between the BC and BI raw, unfiltered call sets (most permissive).