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Table 3 Model-specific miRNAs with their potential mRNA targets

From: Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage

GEM model

Model-specific mmu-miRNA

Number of miRNA probes

Number of target genes

MMTV-c-Myc

494

4

12

 

685

1

8

 

699

1

10

MMTV-H-Ras

182

1

32

 

200c

3

28

 

30b

4

99

MMTV-Wnt1

106b

4

26

 

130a

1

35

 

15a

1

65

 

19b

4

19

 

22

4

22

 

301

1

10

 

335

2

4

MMTV-PyMT

7

2

14

MMTV-Her2/neu

193

3

8

C3(1)/SV40 T/t-antigens

412

1

9

Normal mammary

10b

3

19

 

148a

4

41

 

150

1

4

 

199a

1

19

 

486

4

2

  1. By applying an integrated miRNA-mRNA correlation analysis, mRNA targets are identified for a list of miRNAs associated with normal mammary tissues and individual GEM models. PyMT, polyoma middle T antigen.