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Table 1 Quantitative PCR enrichment measurements from 12 clinical samples

From: Hybrid selection for sequencing pathogen genomes from clinical samples

  Percentage   Parasite [DNA] (pg/μl)  
Sample parasite DNA WGA Pre-hybrid selectiona Post-hybrid selectiona Fold enrichment
Th231.08 (round 1) 0.11 Yes 1.8 (0.6) 71.1 (5.6) 39.7
Th231.08 (round 2) 7.7 No 71.1 (5.6) 349.1 (74.9) 4.9
Th145.08 20 No 198.4 (17.4) 477.6 (66.7) 2.4
Th032.09 12 No 114.7 (2.9) 372.6 (59.3) 3.2
Th029.09 3 No 33.6 (0.8) 317.3 (54.7) 9.4
Th093.09 2.8 No 28.5 (1.5) 365.6 (53.4) 12.8
Th090.08 2.3 No 37.7 (1.1) 300.4 (46.9) 8.0
Th139.08 2.1 No 23.6 (0.6) 346.2 (50.7) 14.7
Th197.08 1.1 No 14.6 (0.0) 222.7 (36.1) 15.3
Th140.08 0.99 No 9.6 (0.1) 251.5 (37.4) 26.2
Th190.08 0.64 No 5.1 (0.2) 218.7 (34.0) 43.2
Th238.08 0.53 No 6.7 (0.2) 273.4 (38.1) 41.0
Th127.09 1.6 No 26.8 (0.4) 368.5 (57.1) 13.7
Th175.08 48 Yes 275.8 (7.2) 556.9 (79.4) 2.0
  1. aNumbers in parentheses represent standard deviations. WGA, whole genome amplification.