Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits

Table 2 Comparison of profiles for RELA-containing dimers

	RELARELA	RELAp50	RELAp52
Proportion of 11-mer sequences shared with RELARELA		61%	63%
Proportion of 11-mer sequences shared with RELAp50			81%
Proportion of 11-mer 'canonical NF-κB binders' (n = 4,399) that are enriched	72% (3,167)^a	84% (3,683)^a	82% (3,599)^a
Proportion of enriched 11-mer sequences that have a MATCH score < 0.5	43% (n = 217,543)	47% (n = 289,319)	61% (n = 281,312)

Similarities between the binding profiles of the three dimers with proportions of 'canonical NF-κB binders' and sequences with MATCH scores < 0.5 present in each. ^aHypergeometric probability test for over-representation: P = 1e-99.

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