Figure 4

Normalized coverage distributions. (a) Coverage of genomic subregions, relative to the CCDS, after whole genome SOLiD sequencing. Green, regions specific to REC-set; orange, regions specific to VCR-set; blue, shared regions. 'R/V specific' refers to RefSeq/Vega exons not contained in the CCDS. (b) Proportional difference in relative coverage between capture-sequencing and WGS shows both enrichment (values > 1) and depletion (values < 1) of certain genomic subregions after capture. Green, regions specific to REC-set; orange, regions specific to VCR-set; blue shared regions.