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Table 3 Differentially expressed kinase transcripts by SAGE

From: The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

ORF

Group

Family

Subfamily

Orthology

Catalytically active?

SAGE cluster

R

Maximum percentage × 1,000

92498

Other

Nek

Nek-Unclassified

1:1:1

Active

Cysts and excyzoites

9.56

38.5

17625

CMGC

GSK

 

1:1:1

Active

Cysts and excyzoites

8.30

43.4

8350

Other

Nek

Nek-Unclassified

1:1:1

Active

Cysts and excyzoites

9.10

44

14835

Other

Nek

Nek-Unclassified

1:1:1

Inactive

Cysts and excyzoites

13.68

44

11364

AGC

Akt

 

1:1:1

Active

Cysts and excyzoites

10.05

63.2

15397

CMGC

CDK

CDC2

1:1:1

Active

Cysts and excyzoites

9.46

71.5

8805

Other

SCY1

 

1:1:1

Inactive

Cysts and excyzoites

13.93

74.3

17578

Other

Nek

Nek-Unclassified

1:1:1

Inactive

Cysts and excyzoites

13.67

77

91451

Other

Nek

Nek-Unclassified

1:1:1

Active

Cysts and excyzoites

19.69

87.9

95593

Other

Nek

Nek-GL2

1:1:1

Active

Cysts and excyzoites

16.11

92.9

3957

Other

Nek

Nek-Unclassified

1:1:1

Active

Cysts and excyzoites

25.71

109.9

114307

Other

Nek

Nek-GL1

1:1:1

Active

Cysts and excyzoites

24.87

111.5

22451

Other

Nek

Nek-Unclassified

1:1:1

Inactive

Cysts and excyzoites

44.93

255.6

113456

Other

VPS15

 

1:1:1

Active

Differentiation

9.40

75.2

101307

Other

Nek

Nek-GL1

3:1:1

Active

Trophozoites and encyzoites

10.11

37.8

86934_mod

Other

Nek

Nek-GL1

3:1:1

Active

Trophozoites and encyzoites

10.11

37.8

16943

Other

Nek

Nek-Unclassified

1:1:1

Inactive

Trophozoites and encyzoites

11.98

39.7

3677

Other

Nek

Nek-GL4

1:1:1

Active

Trophozoites and encyzoites

10.31

54

113030

Other

Nek

Nek-GL4

1:1:1

Inactive

Trophozoites and encyzoites

10.14

59.9

5346

Other

Nek

Nek-Unclassified

1:1:1

Active

Trophozoites and encyzoites

10.59

75.6

101534

Other

Nek

Nek-GL4

C

Active

Trophozoites and encyzoites

18.41

75.6

16824

Other

Nek

Nek-Unclassified

1:1:1

Inactive

Trophozoites and encyzoites

8.76

81.5

90343

Other

WNK

 

1:1:1

Active

Trophozoites and encyzoites

11.42

105.2

114495_mod

Other

Nek

Nek-GL4

C

Pseudogene

Trophozoites and encyzoites

27.04

174.5

24321

Other

Nek

Nek-Unclassified

1:1:1

Inactive

Trophozoites and encyzoites

36.42

213.2

15409

Other

Nek

Nek-Unclassified

1:0:2

Inactive

Trophozoites and encyzoites

35.87

507.4

  1. R is a measure of differential expression, with R = 8 used as a cutoff. Max percentage is the percentage of all SAGE tags belonging to this transcript at its maximum level. ORFs 101307 and 86934_mod are almost identical and share the same SAGE tags. Orthology is the number of orthologous kinases in WB:GS:P15; C means a complex ratio.