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Table 3 Summary of parameter estimates and significance levels of the multivariate generalized linear regression analysis for CpG transversion rate

From: Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content

  Dataset A Dataset B Dataset C
  Estimate -log10(p) Estimate -log10(p) Estimate -log10(p)
Divergence 0.2044 > 15.70 0.1823 > 15.70 0.1414 > 15.70
Methylation level 0.0222 1.14 0.0534 14.88 0.0781 > 15.70
GC content -0.0918 > 15.70 -0.1401 > 15.70 -0.1076 > 15.70
Transcription level -0.0440 3.84 -0.0322 8.15 -0.0336 3.64
Female recombination rate 0.0071 0.26 -0.0084 0.83 0.0044 0.19
Male recombination rate 0.0022 0.07 -0.0006 0.04 -0.0011 0.04
Explained deviance 356 1,421 519
Residual deviance 9,979 15,544 2,986
na 13,038 21,636 3,871
AICb 21,460 50,718 12,684
  1. Dataset A contains no CpG islands (CGIs) or DNase I hypersensitive sites (DHSs)), dataset B contains DHSs but no CGIs, and dataset C contains both CGIs and DHSs. aSample size. bAkaike Information Criterion.